dinuc.cpp
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上传日期:2007-06-13
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- /*
- * ===========================================================================
- * PRODUCTION $Log: dinuc.cpp,v $
- * PRODUCTION Revision 1000.5 2004/06/01 20:54:54 gouriano
- * PRODUCTION PRODUCTION: UPGRADED [GCC34_MSVC7] Dev-tree R1.23
- * PRODUCTION
- * ===========================================================================
- */
- /* $Id: dinuc.cpp,v 1000.5 2004/06/01 20:54:54 gouriano Exp $
- * ===========================================================================
- *
- * PUBLIC DOMAIN NOTICE
- * National Center for Biotechnology Information
- *
- * This software/database is a "United States Government Work" under the
- * terms of the United States Copyright Act. It was written as part of
- * the author's official duties as a United States Government employee and
- * thus cannot be copyrighted. This software/database is freely available
- * to the public for use. The National Library of Medicine and the U.S.
- * Government have not placed any restriction on its use or reproduction.
- *
- * Although all reasonable efforts have been taken to ensure the accuracy
- * and reliability of the software and data, the NLM and the U.S.
- * Government do not and cannot warrant the performance or results that
- * may be obtained by using this software or data. The NLM and the U.S.
- * Government disclaim all warranties, express or implied, including
- * warranties of performance, merchantability or fitness for any particular
- * purpose.
- *
- * Please cite the author in any work or product based on this material.
- *
- * ===========================================================================
- *
- * Authors: Josh Cherry
- *
- * File Description:
- * CAlgoPlugin_Dinuc -- implements the algorithm to calculate dinucleotide frequencies
- */
- #include <ncbi_pch.hpp>
- #include "dinuc.hpp"
- #include "output_dlg.hpp"
- #include <algo/sequence/nuc_prop.hpp>
- #include <gui/core/idocument.hpp>
- #include <gui/core/plugin_utils.hpp>
- #include <gui/core/version.hpp>
- #include <gui/plugin/PluginCommandSet.hpp>
- #include <gui/plugin/PluginInfo.hpp>
- #include <gui/plugin/PluginRequest.hpp>
- #include <gui/plugin/PluginValueConstraint.hpp>
- #include <objects/seqloc/Seq_loc.hpp>
- #include <objmgr/scope.hpp>
- #include <objmgr/seq_vector.hpp>
- #include <objmgr/util/sequence.hpp>
- BEGIN_NCBI_SCOPE
- USING_SCOPE(objects);
- CAlgoPlugin_Dinuc::CAlgoPlugin_Dinuc()
- {
- }
- CAlgoPlugin_Dinuc::~CAlgoPlugin_Dinuc()
- {
- }
- // standard info boilerplate
- void CAlgoPlugin_Dinuc::GetInfo(CPluginInfo& info)
- {
- info.Reset();
- // version info macro
- info.SetInfo(CPluginVersion::eMajor, CPluginVersion::eMinor, 0,
- string(__DATE__) + " " + string(__TIME__),
- "CAlgoPlugin_Dinuc", "Composition/Dinucleotide Frequencies",
- "Determine dinucleotide frequencies",
- "");
- // command info
- CPluginCommandSet& cmds = info.SetCommands();
- CPluginCommand& args = cmds.AddAlgoCommand(eAlgoCommand_run);
- args.AddArgument("locs", "Locations to evaluate",
- CSeq_loc::GetTypeInfo(),
- CPluginArg::TData::e_Array);
- args.SetConstraint("locs",
- (*CPluginValueConstraint::CreateSeqMol(),
- CSeq_inst::eMol_na,
- CSeq_inst::eMol_dna,
- CSeq_inst::eMol_rna));
- }
- void CAlgoPlugin_Dinuc::RunCommand(CPluginMessage& msg)
- {
- const CPluginCommand& args = msg.GetRequest().GetCommand();
- CPluginReply& reply = msg.SetReply();
- _TRACE("CAlgoPlugin_Dinuc::Run()");
- if ( !m_OutputDlg.get() ) {
- m_OutputDlg.reset(new COutputDlg());
- }
- m_OutputDlg->SetTitle("Results: Dinucleotide Frequencies");
- string str;
- //
- // first, evaluate whole sequences
- //
- plugin_args::TLocList locs;
- GetArgValue(args["locs"], locs);
- ITERATE (plugin_args::TLocList, iter, locs) {
- const CSeq_loc& loc = *iter->second;
- const IDocument& doc = *iter->first;
- try {
- CBioseq_Handle handle = doc.GetScope().GetBioseqHandle(loc);
- CSeqVector vec =
- handle.GetSequenceView(loc,
- CBioseq_Handle::eViewConstructed,
- CBioseq_Handle::eCoding_Iupac);
- vector<int> table;
- CNucProp::CountNmers(vec, 2, table);
- // total dimers != length-1 if ambiguity characters
- int sum = 0;
- for( int i = 0; i < 16; i++ ) {
- sum += table[i];
- }
-
- if ( !str.empty() ) {
- str += "n";
- }
-
- const CSeq_id& best_id =
- sequence::GetId(handle, sequence::eGetId_Best);
- best_id.GetLabel(&str);
- str += "t[";
- str += CPluginUtils::GetLabel(loc, &doc.GetScope());
- str += "]n";
- // header
- str += 't';
- int m;
- for(m=0; m<4; m++) {
- str += 't';
- string nuc;
- CNucProp::Int2Nmer(m, 1, nuc);
- str += nuc;
- }
- str += 'n';
- // rest
- for(int n=0; n<4; n++) {
- string nuc;
- CNucProp::Int2Nmer(n, 1, nuc);
- str += nuc;
- for(m=0; m<4; m++) {
- str += 't';
- str += NStr::DoubleToString(table[4*n+m] / (double) sum, 4);
- }
- str += 'n';
- }
- }
- catch (CException& e) {
- string str = CPluginUtils::GetLabel(loc, &doc.GetScope());
- LOG_POST(Error << "Error processing location " << str
- << ": " << e.what());
- }
- #ifndef _DEBUG
- catch (...) {
- string str = CPluginUtils::GetLabel(loc, &doc.GetScope());
- LOG_POST(Error << "Error processing location " << str);
- }
- #endif
- }
- //
- // prepare our dialog box
- //
- if (str.empty()) {
- str = "No relevant selections found.";
- }
- m_OutputDlg->SetText(str);
- m_OutputDlg->Show();
- reply.SetStatus(eMessageStatus_success);
- }
- END_NCBI_SCOPE
- /*
- * ===========================================================================
- * $Log: dinuc.cpp,v $
- * Revision 1000.5 2004/06/01 20:54:54 gouriano
- * PRODUCTION: UPGRADED [GCC34_MSVC7] Dev-tree R1.23
- *
- * Revision 1.23 2004/05/21 22:27:46 gorelenk
- * Added PCH ncbi_pch.hpp
- *
- * Revision 1.22 2004/03/05 17:35:37 dicuccio
- * Use sequence::GetId() instead of CSeq_id::GetStringDescr()
- *
- * Revision 1.21 2004/01/27 18:37:37 dicuccio
- * Code clean-up. Use standard names for plugins. Removed unnecessary #includes
- *
- * Revision 1.20 2004/01/07 15:50:36 dicuccio
- * Adjusted for API change in CPluginUtils::GetLabel(). Standardized exception
- * reporting in algorithms.
- *
- * Revision 1.19 2003/11/24 15:45:25 dicuccio
- * Renamed CVersion to CPluginVersion
- *
- * Revision 1.18 2003/11/06 20:12:12 dicuccio
- * Cleaned up handling of USING_SCOPE - removed from all headers
- *
- * Revision 1.17 2003/11/04 17:49:22 dicuccio
- * Changed calling parameters for plugins - pass CPluginMessage instead of paired
- * CPluginCommand/CPluginReply
- *
- * Revision 1.16 2003/10/07 13:47:00 dicuccio
- * Renamed CPluginURL* to CPluginValue*
- *
- * Revision 1.15 2003/09/04 14:05:24 dicuccio
- * Use IDocument instead of CDocument
- *
- * Revision 1.14 2003/09/03 14:46:53 rsmith
- * change namespace name from args to plugin_args to avoid clashes with variable names.
- *
- * Revision 1.13 2003/08/21 12:03:07 dicuccio
- * Make use of new typedef in plugin_utils.hpp for argument values.
- *
- * Revision 1.12 2003/08/18 15:05:11 jcherry
- * Reflect changes in nuc_prop.?pp. Pre-allocate dialog rows for speed.
- *
- * Revision 1.11 2003/07/28 11:51:48 dicuccio
- * Rewrote CTablePanel<> to be more flexible and better contained. Added standard
- * multicolumn list dialog. Deprecated use of COutputDlg.
- *
- * Revision 1.10 2003/07/22 15:32:16 dicuccio
- * Changed to make use of new API in plugin_utils.hpp - GetArgValue()
- *
- * Revision 1.9 2003/07/21 19:32:53 dicuccio
- * Added constraints based on molecule type
- *
- * Revision 1.8 2003/07/14 11:12:11 shomrat
- * Plugin messageing system related changes
- *
- * Revision 1.7 2003/07/01 15:08:41 jcherry
- * Moved a bunch of stuff into CNucProp and CProtProp
- * Put these in c++/{src,include}/algo/sequence
- *
- * Revision 1.6 2003/06/26 15:33:40 dicuccio
- * Moved GetURLValue() from PluginURL.hpp to plugin_utils.hpp. Fixed compilation
- * errors relating to missing #includes
- *
- * Revision 1.5 2003/06/25 17:02:57 dicuccio
- * Split CPluginHandle into a handle (pointer-to-implementation) and
- * implementation file. Lots of #include file clean-ups.
- *
- * Revision 1.4 2003/06/20 14:52:36 dicuccio
- * Revised plugin registration - moved GetInfo() into the plugin handler
- *
- * Revision 1.3 2003/06/10 17:30:58 jcherry
- * Changed dinucleotide stuff to use n-mer algorithm
- *
- * Revision 1.2 2003/06/09 19:13:51 jcherry
- * Retabbified, etc., to comply with conventions
- *
- * Revision 1.1 2003/06/09 17:29:56 jcherry
- * Initial version
- *
- * ===========================================================================
- */